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Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination

Antigenic variation in Trypanosoma brucei has selected for the evolution of a massive archive of silent Variant Surface Glycoprotein (VSG) genes, which are activated by recombination into specialized expression sites. Such VSG switching can occur at rates substantially higher than background mutatio...

詳細記述

保存先:
書誌詳細
主要な著者: Hartley, Claire L, McCulloch, Richard
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408642/
https://ncbi.nlm.nih.gov/pubmed/18430140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06230.x
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