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Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination
Antigenic variation in Trypanosoma brucei has selected for the evolution of a massive archive of silent Variant Surface Glycoprotein (VSG) genes, which are activated by recombination into specialized expression sites. Such VSG switching can occur at rates substantially higher than background mutatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2408642/ https://ncbi.nlm.nih.gov/pubmed/18430140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06230.x |
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