Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination

Antigenic variation in Trypanosoma brucei has selected for the evolution of a massive archive of silent Variant Surface Glycoprotein (VSG) genes, which are activated by recombination into specialized expression sites. Such VSG switching can occur at rates substantially higher than background mutatio...

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Detalles Bibliográficos
Main Authors: Hartley, Claire L, McCulloch, Richard
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2008
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408642/
https://ncbi.nlm.nih.gov/pubmed/18430140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06230.x
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