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Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons

Members of the Kv7 family (Kv7.2–Kv7.5) generate a subthreshold K(+) current, the M− current. This regulates the excitability of many peripheral and central neurons. Recent evidence shows that Kv7.2 and Kv7.3 subunits are targeted to the axon initial segment of hippocampal neurons by association wit...

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Detalhes bibliográficos
Main Authors: Shah, Mala M., Migliore, Michele, Valencia, Ignacio, Cooper, Edward C., Brown, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408483/
https://ncbi.nlm.nih.gov/pubmed/18515424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802805105
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