l-Arginine Decreases Inflammation and Modulates the Nuclear Factor-κB/Matrix Metalloproteinase Cascade in Mdx Muscle Fibers

Duchenne muscular dystrophy (DMD) is a lethal, X-linked disorder associated with dystrophin deficiency that results in chronic inflammation, sarcolemma damage, and severe skeletal muscle degeneration. Recently, the use of l-arginine, the substrate of nitric oxide synthase (nNOS), has been proposed a...

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Autors principals: Hnia, Karim, Gayraud, Jérôme, Hugon, Gérald, Ramonatxo, Michèle, De La Porte, Sabine, Matecki, Stefan, Mornet, Dominique
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2008
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408412/
https://ncbi.nlm.nih.gov/pubmed/18458097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071009
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