Modulation of p38 Mitogen-Activated Protein Kinase Cascade and Metalloproteinase Activity in Diaphragm Muscle in Response to Free Radical Scavenger Administration in Dystrophin-Deficient Mdx Mice

Duchenne muscular dystrophy muscles undergo increased oxidative stress and altered calcium homeostasis, which contribute to myofiber loss by trigging both necrosis and apoptosis. Here, we asked whether treatment with free radical scavengers could improve the dystrophic pattern of mdx muscles. Five-w...

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Detalhes bibliográficos
Main Authors: Hnia, Karim, Hugon, Gerald, Rivier, François, Masmoudi, Ahmed, Mercier, Jacques, Mornet, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851881/
https://ncbi.nlm.nih.gov/pubmed/17255331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060344
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