The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia

The serine proteases tissue plasminogen activator, plasmin, and thrombin and their receptors have previously been suggested to contribute to neuronal damage in certain pathological situations. Here we demonstrate that mice lacking protease-activated receptor 1 (PAR1) have a 3.1-fold reduction in inf...

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Autors principals: Junge, Candice E., Sugawara, Taku, Mannaioni, Guido, Alagarsamy, Sudar, Conn, P. Jeffrey, Brat, Daniel J., Chan, Pak H., Traynelis, Stephen F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC240737/
https://ncbi.nlm.nih.gov/pubmed/14559973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2235594100
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