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The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia

The serine proteases tissue plasminogen activator, plasmin, and thrombin and their receptors have previously been suggested to contribute to neuronal damage in certain pathological situations. Here we demonstrate that mice lacking protease-activated receptor 1 (PAR1) have a 3.1-fold reduction in inf...

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Hlavní autoři: Junge, Candice E., Sugawara, Taku, Mannaioni, Guido, Alagarsamy, Sudar, Conn, P. Jeffrey, Brat, Daniel J., Chan, Pak H., Traynelis, Stephen F.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC240737/
https://ncbi.nlm.nih.gov/pubmed/14559973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2235594100
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