Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid

The exceptional sensitivity of Mycobacterium tuberculosis to isonicotinic acid hydrazide (INH) lacks satisfactory definition. M. tuberculosis is a natural mutant in oxyR, a central regulator of peroxide stress response. The ahpC gene, which encodes a critical subunit of alkyl hydroperoxide reductase...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zhang, Y., Dhandayuthapani, S., Deretic, V.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24072/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.13212
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!