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Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer

This article extends our previous quantitative analysis of the relationship between the dynamics of the primary structure of DNA and mutagenesis associated with single-strand lesions to an analysis of the production and processing of endogenous double-strand breaks (EDSBs) and to their implications...

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Bibliografiske detaljer
Main Authors: Vilenchik, Michael M., Knudson, Alfred G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC240711/
https://ncbi.nlm.nih.gov/pubmed/14566050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2135498100
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