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Evolutionary specialization of a tryptophan indole group for transition-state stabilization by eukaryotic transglutaminases
Covalent posttranslational protein modifications by eukaryotic transglutaminases proceed by a kinetic pathway of acylation and deacylation. Ammonia is released as the acylenzyme is formed, whereas the cross-linked product is released later in the deacylation step. Superposition of the active sites o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC240670/ https://ncbi.nlm.nih.gov/pubmed/14566064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1635052100 |
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