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AIPL1, a protein implicated in Leber's congenital amaurosis, interacts with and aids in processing of farnesylated proteins

The most common form of blindness at birth, Leber's congenital amaurosis (LCA), is inherited in an autosomal recessive fashion. Mutations in six different retina-specific genes, including a recently discovered gene, AIPL1, have been linked to LCA in humans. To understand the molecular basis of...

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Main Authors: Ramamurthy, Visvanathan, Roberts, Melanie, van den Akker, Focco, Niemi, Gregory, Reh, T. A., Hurley, James B.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC240669/
https://ncbi.nlm.nih.gov/pubmed/14555765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2134194100
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