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Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins

Large-scale motions of biomolecules involve linear elastic deformations along low-frequency normal modes, but for function nonlinearity is essential. In addition, unlike macroscopic machines, biological machines can locally break and then reassemble during function. We present a model for global str...

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Detaylı Bibliyografya
Asıl Yazarlar: Miyashita, O., Onuchic, J. N., Wolynes, P. G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC240658/
https://ncbi.nlm.nih.gov/pubmed/14566052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2135471100
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