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DNA-mediated charge transport for DNA repair

MutY, like many DNA base excision repair enzymes, contains a [4Fe4S](2+) cluster of undetermined function. Electrochemical studies of MutY bound to a DNA-modified gold electrode demonstrate that the [4Fe4S] cluster of MutY can be accessed in a DNA-mediated redox reaction. Although not detectable wit...

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Détails bibliographiques
Auteurs principaux: Boon, Elizabeth M., Livingston, Alison L., Chmiel, Nikolas H., David, Sheila S., Barton, Jacqueline K.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC240652/
https://ncbi.nlm.nih.gov/pubmed/14559969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2035257100
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