Identification of neutralizing antigenic sites on VP1 and VP2 of type A5 foot-and-mouth disease virus, defined by neutralization-resistant variants.

Five neutralizing monoclonal antibodies (nMAbs) obtained against type A5 Spain-86 foot-and-mouth disease virus were used to generate a series of neutralization-resistant variants. In vitro and in vivo assays showed that the variants were fully refractory to neutralization by the selecting nMAb. On t...

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Bibliografiska uppgifter
Huvudupphovsmän: Saiz, J C, Gonzalez, M J, Borca, M V, Sobrino, F, Moore, D M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC240607/
https://ncbi.nlm.nih.gov/pubmed/1707983
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