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Reduced nonprotein thiols inhibit activation and function of MMP-9: Implications for chemoprevention

Clinical studies demonstrate a positive correlation between the extent of matrix metalloproteinase (MMP) activation and malignant progression of precancerous lesions. Therefore, identification of effective, well-tolerated MMP inhibitors represents a rational chemopreventive strategy. A variety of ag...

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Detalhes bibliográficos
Main Authors: Pei, Ping, Horan, Michael P., Hille, Russ, Hemann, Craig F., Schwendeman, Steven P., Mallery, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2405910/
https://ncbi.nlm.nih.gov/pubmed/17015178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.07.014
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