Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4

Absence epilepsy, characterized by spike–wave discharges (SWD) in the electroencephalogram, arises from aberrations within the circuitry of the cerebral cortex and thalamus that regulates awareness. The inbred mouse strain C3H/HeJ is prone to absence seizures, with a major susceptibility locus, spkw...

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Huvudupphovsmän: Beyer, Barbara, Deleuze, Charlotte, Letts, Verity A., Mahaffey, Connie L., Boumil, Rebecca M., Lew, Timothy A., Huguenard, John R., Frankel, Wayne N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2008
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2405903/
https://ncbi.nlm.nih.gov/pubmed/18316356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn064
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