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Antibodies to the trypsin cleavage peptide VP8 neutralize rotavirus by inhibiting binding of virions to target cells in culture.

Two distinct patterns of neutralization were identified by comparing the neutralization curves of monoclonal antibodies (MAbs) directed at the two surface proteins, VP4 and VP7, of rhesus rotavirus. VP7-specific MAbs were able to neutralize virus efficiently, and slight increases in antibody concent...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Ruggeri, F M, Greenberg, H B
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1991
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240568/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850007/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.5.2211-2219.1991
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