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Antibodies to the trypsin cleavage peptide VP8 neutralize rotavirus by inhibiting binding of virions to target cells in culture.

Two distinct patterns of neutralization were identified by comparing the neutralization curves of monoclonal antibodies (MAbs) directed at the two surface proteins, VP4 and VP7, of rhesus rotavirus. VP7-specific MAbs were able to neutralize virus efficiently, and slight increases in antibody concent...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Ruggeri, F M, Greenberg, H B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240568/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850007/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.5.2211-2219.1991
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