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The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells.

The contribution of the E6 and E7 open reading frames of human papillomavirus type 6b (HPV6b) and HPV16 to immortalization of human keratinocytes was evaluated by using amphotropic recombinant retroviruses. The HPV16 E7 gene could immortalize primary human keratinocytes without the cooperation of th...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Halbert, C L, Demers, G W, Galloway, D A
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1845902/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.1.473-478.1991
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