Pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of CD4+ T cells.

In previous studies, it was observed that children immunized with a formalin-inactivated respiratory syncytial virus vaccine (FI-RSV) developed severe pulmonary disease with greater frequency during subsequent natural RSV infection than did controls. During earlier efforts to develop an animal model...

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Detalhes bibliográficos
Main Authors: Connors, M, Kulkarni, A B, Firestone, C Y, Holmes, K L, Morse, H C, Sotnikov, A V, Murphy, B R
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC240452/
https://ncbi.nlm.nih.gov/pubmed/1433525
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