Pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of CD4+ T cells.

In previous studies, it was observed that children immunized with a formalin-inactivated respiratory syncytial virus vaccine (FI-RSV) developed severe pulmonary disease with greater frequency during subsequent natural RSV infection than did controls. During earlier efforts to develop an animal model...

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Pubblicato in:	J Virol
Autori principali:	Connors, M, Kulkarni, A B, Firestone, C Y, Holmes, K L, Morse, H C, Sotnikov, A V, Murphy, B R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240452/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1433525/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.12.7444-7451.1992
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