Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid protein.

Residues 11 to 27 of the hepatitis B virus nucleocapsid antigen contain a cytotoxic T-cell epitope that is recognized by cytotoxic T cells from virtually all HLA-A2-positive patients with acute hepatitis B virus infection. Using panels of truncated and overlapping peptides, we now show that the opti...

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Pubblicato in:	J Virol
Autori principali:	Bertoletti, A, Chisari, F V, Penna, A, Guilhot, S, Galati, L, Missale, G, Fowler, P, Schlicht, H J, Vitiello, A, Chesnut, R C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7680391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2376-2380.1993
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