Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid protein.

Residues 11 to 27 of the hepatitis B virus nucleocapsid antigen contain a cytotoxic T-cell epitope that is recognized by cytotoxic T cells from virtually all HLA-A2-positive patients with acute hepatitis B virus infection. Using panels of truncated and overlapping peptides, we now show that the opti...

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Autors principals: Bertoletti, A, Chisari, F V, Penna, A, Guilhot, S, Galati, L, Missale, G, Fowler, P, Schlicht, H J, Vitiello, A, Chesnut, R C
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC240403/
https://ncbi.nlm.nih.gov/pubmed/7680391
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