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Replication of hepatitis delta virus RNA: effect of mutations of the autocatalytic cleavage sites.

Hepatitis delta virus (HDV) contains a circular RNA genome of 1.7 kb. HDV RNA replication is thought to proceed via a rolling-circle mechanism that is dependent on autocatalytic cleavage and ligation reactions. However, it has never been established that these ribozyme activities are indeed involved...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Macnaughton, T B, Wang, Y J, Lai, M M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240348/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8445730/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2228-2234.1993
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