Construction and properties of a recombinant herpes simplex virus 1 lacking both S-component origins of DNA synthesis.

The herpes simplex virus 1 (HSV-1) genome contains three origins of DNA synthesis (Ori) utilized by viral DNA synthesis proteins. One sequence (OriI) maps in the L component, whereas two sequences (OriS) map in the S component. We report the construction of a recombinant virus, R7711, from which bot...

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Bibliographic Details
Main Authors: Igarashi, K, Fawl, R, Roller, R J, Roizman, B
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC240309/
https://ncbi.nlm.nih.gov/pubmed/8383234
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