Role of maturation cleavage in infectivity of picornaviruses: activation of an infectosome.

Maturation of picornaviruses involves assembly of a "provirion," which undergoes an autocatalytic cleavage of VP0 to VP2 plus VP4. RNA transcripts from a cDNA clone of human rhinovirus 14 mutated at asparagine 68, one of the residues in the maturation cleavage site, generated normal yields of 150S p...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Lee, W M, Monroe, S S, Rueckert, R R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2110-2122.1993
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