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Role of maturation cleavage in infectivity of picornaviruses: activation of an infectosome.

Maturation of picornaviruses involves assembly of a "provirion," which undergoes an autocatalytic cleavage of VP0 to VP2 plus VP4. RNA transcripts from a cDNA clone of human rhinovirus 14 mutated at asparagine 68, one of the residues in the maturation cleavage site, generated normal yields...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Lee, W M, Monroe, S S, Rueckert, R R
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240305/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383233/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2110-2122.1993
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