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Role of maturation cleavage in infectivity of picornaviruses: activation of an infectosome.
Maturation of picornaviruses involves assembly of a "provirion," which undergoes an autocatalytic cleavage of VP0 to VP2 plus VP4. RNA transcripts from a cDNA clone of human rhinovirus 14 mutated at asparagine 68, one of the residues in the maturation cleavage site, generated normal yields...
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| Gepubliceerd in: | J Virol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
1993
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2110-2122.1993 |
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