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Translational stimulation by reovirus polypeptide sigma 3: substitution for VAI RNA and inhibition of phosphorylation of the alpha subunit of eukaryotic initiation factor 2.

COS cells transfected with plasmids that activate DAI depend on expression of virus-associated I (VAI) RNA to prevent the inhibitory effects of the alpha subunit of eukaryotic initiation factor 2 (eIF-2 alpha) kinase (DAI) and restore the translation of vector-derived dihydrofolate reductase mRNA. T...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Lloyd, R M, Shatkin, A J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1992
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1433498/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.12.6878-6884.1992
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