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Reovirus polypeptide sigma 3 and N-terminal myristoylation of polypeptide mu 1 are required for site-specific cleavage to mu 1C in transfected cells.

N-myristoylated viral polypeptide mu 1 was produced in COS cells transfected with a transient expression vector containing a DNA copy of the reovirus M2 gene. The mu 1 product was specifically cleaved to polypeptide mu 1C in cells that were cotransfected with the reovirus S4 gene and that expressed...

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Publicado en:J Virol
Autores principales: Tillotson, L, Shatkin, A J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1992
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289010/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1548757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.2180-2186.1992
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