The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane protein 2 (LMP2) are dispensable for lymphocyte infection and growth transformation in vitro.

Specifically mutated Epstein-Barr virus (EBV) recombinants which truncate latent membrane protein 2A (LMP2A) and LMP2B after 260 of 497 amino acids and after 141 of 378 amino acids, respectively, were constructed. Despite truncation before the last seven transmembrane domains and the carboxy terminu...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Longnecker, R, Miller, C L, Miao, X Q, Tomkinson, B, Kieff, E
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240269/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383224/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.4.2006-2013.1993
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