In vitro enzymatic activity of human immunodeficiency virus type 1 reverse transcriptase mutants in the highly conserved YMDD amino acid motif correlates with the infectious potential of the proviral genome.

Reverse transcriptases contain a highly conserved YXDD amino acid motif believed to be important in enzyme function. The second amino acid is not strictly conserved, with a methionine, valine or alanine occupying the second position in reverse transcriptases from various retroviruses and retroelemen...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wakefield, J K, Jablonski, S A, Morrow, C D
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC240183/
https://ncbi.nlm.nih.gov/pubmed/1383571
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires