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Design of high-affinity major histocompatibility complex-specific antagonist peptides that inhibit cytotoxic T-lymphocyte activity: implications for control of viral disease.

Cytotoxic T lymphocytes (CTLs) recognize viral antigens presented by infected cells in the context of their major histocompatibility complex glycoproteins. The irreversible killing of virus-infected cells by virus-specific CTLs can be the cause of serious disease, particularly in the central nervous...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Gairin, J E, Oldstone, M B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6755-6762.1992
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