Design of high-affinity major histocompatibility complex-specific antagonist peptides that inhibit cytotoxic T-lymphocyte activity: implications for control of viral disease.

Cytotoxic T lymphocytes (CTLs) recognize viral antigens presented by infected cells in the context of their major histocompatibility complex glycoproteins. The irreversible killing of virus-infected cells by virus-specific CTLs can be the cause of serious disease, particularly in the central nervous...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Gairin, J E, Oldstone, M B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6755-6762.1992
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