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Oligomerization of hepatitis delta antigen is required for both the trans-activating and trans-dominant inhibitory activities of the delta antigen.

Two forms of hepatitis delta antigen (HDAg) have different roles in the replication cycle of hepatitis delta virus (HDV); the small forms trans activates HDV RNA replication, whereas the large form suppresses it but is needed for virion assembly. To understand the mechanism of these regulatory activ...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Xia, Y P, Lai, M M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1404608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6641-6648.1992
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