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Oligomerization of hepatitis delta antigen is required for both the trans-activating and trans-dominant inhibitory activities of the delta antigen.

Two forms of hepatitis delta antigen (HDAg) have different roles in the replication cycle of hepatitis delta virus (HDV); the small forms trans activates HDV RNA replication, whereas the large form suppresses it but is needed for virion assembly. To understand the mechanism of these regulatory activ...

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Библиографические подробности
Главные авторы: Xia, Y P, Lai, M M
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC240160/
https://ncbi.nlm.nih.gov/pubmed/1404608
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