Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell-tropic isolates: definition of critical amino acids involved in cell tropism.

Previous experiments indicate that the V3 hypervariable region of the human immunodeficiency virus (HIV) envelope protein influences cell tropism of infection; however, so far no consistent V3 sequence can account for macrophage or T-cell tropism. In these experiments, we studied infectious recombin...

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Bibliographic Details
Published in:J Virol
Main Authors: Chesebro, B, Wehrly, K, Nishio, J, Perryman, S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240149/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1404602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6547-6554.1992
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