Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophages.

Infectious recombinant viruses were constructed from three molecularly cloned human immunodeficiency virus (HIV) strains varying in cell tropism. All recombinants showed a high infectivity titer on phytohemagglutinin-stimulated normal T lymphocytes. However, a 120-bp region of the envelope gene incl...

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Veröffentlicht in:J Virol
Hauptverfasser: Chesebro, B, Nishio, J, Perryman, S, Cann, A, O'Brien, W, Chen, I S, Wehrly, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1991
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250239/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1920616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.11.5782-5789.1991
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