Mutations within the 5' nontranslated region of hepatitis A virus RNA which enhance replication in BS-C-1 cells.

Passage of human hepatitis A virus (HAV) in cell culture results in attenuation of the virus as well as progressive increases in the efficiency of virus replication in cell culture. Because the presence of identical mutations within the 5' nontranslated regions (5'NTRs) of several independ...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Day, S P, Murphy, P, Brown, E A, Lemon, S M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240147/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1404601/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6533-6540.1992
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