Mutations within the 5' nontranslated region of hepatitis A virus RNA which enhance replication in BS-C-1 cells.

Passage of human hepatitis A virus (HAV) in cell culture results in attenuation of the virus as well as progressive increases in the efficiency of virus replication in cell culture. Because the presence of identical mutations within the 5' nontranslated regions (5'NTRs) of several independently isol...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Day, S P, Murphy, P, Brown, E A, Lemon, S M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1404601/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6533-6540.1992
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