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Studies using double mutants of the conformational transitions in influenza hemagglutinin required for its membrane fusion activity

Amino acid substitutions widely distributed throughout the influenza hemagglutinin (HA) influence the pH of its membrane fusion activity. We have combined a number of these substitutions in double mutants and determined the effects on the pH of fusion and on the pH at which the refolding of HA requi...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Steinhauer, David A., Martín, Javier, Lin, Yi Pu, Wharton, Stephen A., Oldstone, Michael B. A., Skehel, John J., Wiley, Don C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1996
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24013/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917512/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.12873
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