Studies using double mutants of the conformational transitions in influenza hemagglutinin required for its membrane fusion activity

Amino acid substitutions widely distributed throughout the influenza hemagglutinin (HA) influence the pH of its membrane fusion activity. We have combined a number of these substitutions in double mutants and determined the effects on the pH of fusion and on the pH at which the refolding of HA requi...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Steinhauer, David A., Martín, Javier, Lin, Yi Pu, Wharton, Stephen A., Oldstone, Michael B. A., Skehel, John J., Wiley, Don C.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1996
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917512/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.12873
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