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The R-U5-5' leader sequence of neurovirulent wild mouse retrovirus contains an element controlling the incubation period of neurodegenerative disease.

The wild mouse ecotropic retrovirus CasBrE causes a spongiform neurodegenerative disease after neonatal inoculation, with an incubation period ranging from 2 to 12 months. We previously showed that introduction of long terminal repeat (LTR) and gag-pol sequences from a strain of Friend murine leukem...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Portis, J L, Perryman, S, McAtee, F J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2002548/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.4.1877-1883.1991
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