Naturally occurring missense mutation in the polymerase gene terminating hepatitis B virus replication.
A hepatitis B virus (HBV) genome was cloned from human liver. Numerous mutations in all viral genes define this HBV DNA as a mutant, divergent from all known HBV DNA sequences. Functional analyses of this mutant demonstrated a defect blocking viral DNA synthesis. The genetic basis of this defect was...
Gespeichert in:
| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1991
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2002544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.4.1836-1842.1991 |
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