Novel dimeric interface and electrostatic recognition in bacterial Cu,Zn superoxide dismutase

Eukaryotic Cu,Zn superoxide dismutases (CuZnSODs) are antioxidant enzymes remarkable for their unusually stable β-barrel fold and dimer assembly, diffusion-limited catalysis, and electrostatic guidance of their free radical substrate. Point mutations of CuZnSOD cause the fatal human neurodegenerativ...

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Autors principals: Bourne, Yves, Redford, Susan M., Steinman, Howard M., Lepock, James R., Tainer, John A., Getzoff, Elizabeth D.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1996
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23996/
https://ncbi.nlm.nih.gov/pubmed/8917495
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