HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery

Integration of the double-stranded DNA copy of the HIV-1 genome into host chromosomal DNA is a requirement for efficient viral replication. Integration preferentially occurs within active transcription units, however chromosomal site specificity does not correlate with any strong primary sequence. T...

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Bibliographic Details
Main Authors: Albanese, Alberto, Arosio, Daniele, Terreni, Mariaelena, Cereseto, Anna
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2398779/
https://ncbi.nlm.nih.gov/pubmed/18545681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002413
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