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Protease sensitivity and nuclease resistance of the scrapie agent propagated in vitro in neuroblastoma cells.

The scrapie agent has been propagated in vitro in mouse neuroblastoma cells. To further characterize the tissue culture-derived scrapie agent, we studied the effects of protease and nuclease digestion on the agent derived from these cells. The scrapie agent in these cells was found to be resistant t...

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Main Authors: Neary, K, Caughey, B, Ernst, D, Race, R E, Chesebro, B
Formato: Artigo
Idioma:Inglês
Publicado: 1991
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC239853/
https://ncbi.nlm.nih.gov/pubmed/1846182
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