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Sindbis virus nsP1 functions in negative-strand RNA synthesis.

A mutation at nucleotide 1101 of Sindbis virus ts11 nsP1 caused temperature-sensitive negative-strand synthesis and suppressed the 24R phenotype, which is caused by a mutation in nsP4. Nonstructural proteins synthesized and accumulated by ts11 at 40 degrees C did not cause the reactivation of negati...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Wang, Y F, Sawicki, S G, Sawicki, D L
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1991
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239844/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1824787/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.2.985-988.1991
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