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Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start site.

Repression of human cytomegalovirus alpha (immediate-early) gene expression is under the control of the viral ie2 gene. Here we show that ie2 negatively regulates gene expression directed by the strong cytomegalovirus enhancer via a specific 15-bp target sequence (which we term cis repression signal...

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Bibliografiske detaljer
Main Authors: Cherrington, J M, Khoury, E L, Mocarski, E S
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC239829/
https://ncbi.nlm.nih.gov/pubmed/1846203
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