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Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start site.

Repression of human cytomegalovirus alpha (immediate-early) gene expression is under the control of the viral ie2 gene. Here we show that ie2 negatively regulates gene expression directed by the strong cytomegalovirus enhancer via a specific 15-bp target sequence (which we term cis repression signal...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Cherrington, J M, Khoury, E L, Mocarski, E S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846203/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.2.887-896.1991
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