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Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

INTRODUCTION: The phenotypic and functional differences between cells that initiate human breast tumors (cancer stem cells) and those that comprise the tumor bulk are difficult to study using only primary tumor tissue. We embarked on this study hypothesizing that breast cancer cell lines would conta...

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Detalhes bibliográficos
Main Authors: Fillmore, Christine M, Kuperwasser, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397524/
https://ncbi.nlm.nih.gov/pubmed/18366788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1982
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