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Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system

BACKGROUND: Cancer treatment with a variety of chemotherapeutic agents often is associated with delayed adverse neurological consequences. Despite their clinical importance, almost nothing is known about the basis for such effects. It is not even known whether the occurrence of delayed adverse effec...

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Autores principales: Han, Ruolan, Yang, Yin M, Dietrich, Joerg, Luebke, Anne, Mayer-Pröschel, Margot, Noble, Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397490/
https://ncbi.nlm.nih.gov/pubmed/18430259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol69
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